Product Details
Product name: Triethylene Glycol Monobutyl Ether
Other name:TRIFLUOROMETHANESULFONYLCHLORIDE;TRIFLUOROMETHANESULPHONYLCHLORIDE;TRIFLYLCHLORIDE;Methanesulfonylchloride,trifluoro-;PFC-MSC;TrifluoromaChemicalbookthanesulfonylchloride;Trifluoromethanesulphonylchloride,99%;trifluoromethylsulfonylchloride
CAS No:421-83-0
Molecular Formula:CClF3O2S
Molecular weight:168.52
EINECS No:207-009-0
Trifluoromethanesulfonyl chloride can be used as a pharmaceutical intermediate, such as the preparation of resveratrol trimethyl ether, which is an important synthetic raw material for many antibacterial drugs, weight loss drugs, anticancer drugs and auxiliary agents. For example, the preparation of H-PGDS inhibitors, Rho-kinase inhibitors, KSP inhibitors, CSF-1R inhibitors, renin inhibitors, etc. with anticancer Chemicalbook effects. Trifluoromethanesulfonyl chloride can be prepared by reacting trifluoromethanesulfonic acid with thionyl chloride.
1) Preparation of trifluoromethylsulfonyl fluoride from trifluoromethylsulfonyl chloride. Trifluoromethanesulfonyl fluoride is an important organic intermediate, which can be used to prepare important organic compounds such as trifluoromethanesulfonic acid, trifluoromethylsulfonate, bis(trifluoromethylsulfonyl)imide salt, etc. , It is also an indispensable basic raw material for the synthesis of many pharmaceutical compounds and organic catalysts. As an important fine chemical intermediate, there is a great demand for trifluoromethanesulfonyl fluoride at home and abroad, and it is increasingly becoming a hot product in the field of fine chemical intermediates.
2) Preparation of bistrifluoromethanesulfonylimide lithium salt, including the following steps in Chemicalbook: dissolving benzylamine in an organic solvent, and performing sulfonamide reaction with trifluoromethanesulfonyl chloride or trifluoromethanesulfonyl fluoride , to obtain benzyl bistrifluoromethanesulfonamide, and then reduce to obtain bistrifluoromethanesulfonamide; the resulting bistrifluoromethanesulfonamide is carried out with resin lithium under anhydrous solvent conditions The final product, lithium bistrifluoromethanesulfonylimide, is obtained by ion exchange; the raw materials of this method are cheap and easy to obtain, the reaction steps are simple, the yield is high, there is almost no pollution, no harsh and dangerous reaction conditions, the product is easy to purify, and is suitable for domestic Mass production.
Specifications
Product name:Triethylene Glycol Monobutyl Ether | Othername TRIFLUOROMETHANESULFONYLCHLORIDE; TRIFLUOROMETHANESULPHONYLCHLORIDE; TRIFLYLCHLORIDE;Methanesulfonylchloride,trifluoro-;PFC-MSC;TrifluoromaChemicalbookthanesulfonylchloride; Trifluoromethanesulphonylchloride,99%;trifluoromethylsulfonylchloride |
CAS No:421-83-0 |
Molecular FormulaCClF3O2S | Molecular weight168.52 | EINECS No207-009-0 |
Key Features
- ISO9001
- High Purity
- COA, MSDS available.